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ce of the wire was taken out until finally the total length thus removed aggregated 11 feet； the longest piece measuring two feet and the shortest 1/4 inch。 The wire was found imbedded under the muscles of the arm； and some of it had become wedged between the bones of the forearm。 Probably the most remarkable feature of this curious accident was the fact that there was no fracture or injury to the bone； and it was thought possible that the function of the arm would be but little impaired。
Tousey reports a case of foreign body in the axilla that was taken for a necrotic fragment of the clavicle。 The patient was a boy of sixteen； who climbed up a lamp…post to get a light for his bicycle lamp； his feet slipped off the ornamental ledge which passed horizontally around the post about four feet from the ground； and he fell。 In the fall a lead pencil in his waistcoat pocket caught on the ledge and was driven into the axilla； breaking off out of sight。 This was supposed to be a piece of the clavicle； and was only discovered to be a pencil when it was removed six weeks after。
There are several diseases of the bone having direct bearing on the anomalies of the extremities which should have mention here。 Osteomalacia is a disease of the bones in adult life； occurring most frequently in puerperal women； but also seen in women not in the puerperal state； and in men。 It is characterized by a progressive softening of the bone…substance； from a gradual absorption of the lime salts； and gives rise to considerable deformity； and occasionally to spontaneous fracture。
Rachitis or rickets is not a disease of adult life； but of infancy and childhood； and never occurs after the age of puberty。 It seldom begins before six months or after three years。 There are several theories as to its causation； one being that it is due to an abnormal development of acids。 There is little doubt that defective nutrition and bad hygienic surroundings are prominent factors in its production。 The principal pathologic change is seen in the epiphyseal lines of long bones and beneath the periosteum。 Figure 213 shows the appearance during life of a patient with the highest grade of rachitis； and it can be easily understood what a barrier to natural child…birth it would produce。 In rachitis epiphyseal swellings are seen at the wrists and ankle…joints； and in superior cases at the ends of the phalanges of the fingers and toes。 When the shaft of a long bone is affected； not only deformity； but even fracture may occur。 Under these circumstances the humerus and femur appear to be the bones most likely to break； there is an associate deformity of the head； known as 〃craniotabes；〃 together with pigeon…breast and various spinal curvature。 The accompanying illustration is from a drawing of a skeleton in the Warren Museum in Boston。 The subject was an Indian； twenty…one years of age； one of the Six Nations。 His mode of locomotion was by a large wooden bowl； in which he sat and moved forward by advancing first one side of the bowl and then the other； by means of his hands。 The nodules or 〃adventitious joints〃 were the result of imperfect ossification； or； in other words； of motion before ossification was completed。
Analogous to rachitis is achondroplasia； or the so called fetal ricketsa disease in which deformity results from an arrest； absence； or perversion of the normal process of enchondral ossification。 It is decidedly an intrauterine affection； and the great majority of fetuses die in utero。 Thomson reports three living cases of achondroplasia。 The first was a child five months of age； of pale complexion； bright and intelligent； its head measuring 23 inches in length。 There was a narrow thorax showing the distinct beads of rickets； the upper and lower limbs were very short； but improved under antirachitic treatment。 The child died of pneumonia。 The other two cases were in adults； one thirty…nine and the other thirty…six。 The men were the same height； 49 inches； and resembled each other in all particulars。 They both enjoyed good health； and； though somewhat dwarfed； were of considerable intelligence。 Neither had married。 Both the upper and； lower limbs showed exaggerations of the normal curves； the hands and feet were broad and short； the gait of both of these little men was waddling； the hunk swaying when they attempted to make any rapid progress。
Osteitis deformans is a hyperplasia of bone described by Paget in 1856。 Paget's patient was a gentleman of forty…six who had always enjoyed good health； without assignable cause he began to be subject to aching pains in the thighs and legs。 The bones of the left leg began to increase in size； and a year or two later the left femur； also enlarged considerably。 During a period of twenty years these changes were followed by a growth of other bones。 The spine became firm and； rigid； the head increased 5 1/4 inches in circumference。 The bones of the face were not affected。 When standing； the patient had a peculiar bowed condition of the legs； with marked flexure at the knees。 He finally died of osteosarcoma； originating in the left radius； Paget collected eight cases； five of whom died of malignant disease。 The postmortem of Paget's case showed extreme thickening in the bones affected； the femur and cranium particularly showing osteoclerosis。 Several cases have been recorded in this country； according to Warren； Thieberge analyzed 43 cases； 21 were men； 22 women； the disease appeared usually after forty。
Acromegaly is distinguished from osteitis deformans in that it is limited to hypertrophy of the hands； feet； and face； and it usually begins earlier。 In gigantism the so…called 〃giant growth of bones〃 is often congenital in character； and is unaccompanied by inflammatory symptoms。
The deformities of the articulations may be congenital but in most cases are acquired。 When these are of extreme degree； locomotion is effected in most curious ways。 Ankylosis at unnatural angles and even complete reversion of the joints has been noticed。 Pare gives a case of reversion； and of crooked hands and feet； and Barlow speaks of a child of two and three…quarter years with kyphosis； but mobility of the lumbar region； which walked on its elbows and knees。 The pathology of this deformity is obscure； but there might have been malposition in utero。 Wilson presented a similar case before the Clinical Society of London； in 1888。 The 〃Camel…boy；〃 exhibited some years ago throughout the United States； had reversion of the joints； which resembled those of quadrupeds。 He walked on all fours； the mode of progression resembling that of a camel。
Figure 216 represents Orloff； 〃the transparent man；〃 an exhibitionist； showing curious deformity of the long bones and atrophy of the extremities。 He derived his name from the remarkable transparency of his deformed members to electric light； due to porosity of the bones and deficiency of the overlying tissues。
Figure 217； taken from Hutchinson's 〃Archives of Surgery；〃 represents an extreme case of deformity of the knee…joints in a boy of seven； the result of severe osteoarthritis。 The knees and elbows were completely ankylosed。
Infantile spinal paralysis is often the cause of distressing deformities；